Brown adipose tissue (BAT) dissipates energy and promotes cardio-metabolic health. In this publication, Nieman et al identifiy inosine as novel tissue-messenger in brown fat (BAT). They show that treatment of mice with inosine increased BAT-dependent energy expenditure and induced “browning” of white adipose tissue. This work is funded by the DFG.
Publikation in Nature Publikation in Nature
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© Michelle Y. Jaeckstein and Jörg Heeren, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany
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Niemann, B., Haufs-Brusberg, S., Puetz, L. et al. Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine. Nature (2022).
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine | Nature